José Mourinho has lost only three of his 10 visits to Anfield, the last in the 2007 Champions League semi-final, but the implications of a fourth would be sizeable for both Manchester United and Liverpool. Defeat for United would leave them six points behind their fierce north-west rivals and encourage the portrayal of Mourinho as a manager left behind by the pressing instincts of Jürgen Klopp and co, despite being only eight league matches into his Old Trafford reign. Klopp has injury concerns, however, over two thirds of his central midfield in Adam Lallana and Georginio Wijnaldum. Andy Hunter

Kick-off Monday 8pm

Venue Anfield

Last season Liverpool 0 Manchester United 1

Live Sky Sports 1

Referee Anthony Taylor

This season G7, Y23, R0, 3.29 cards per game

Odds H 6-5 A 5-2 D 12-5

Liverpool

Subs from Mignolet, Manninger, Klavan, Sturridge, Can, Moreno, Lucas, Ings, Stewart, Randall, Grujic, Brannagan, Origi, Ejaria, Ojo

Doubtful Lallana (groin), Wijnaldum (hip)

Injured Gomez (achilles, 29 Oct)

Suspended None

Form LDWWWW

Discipline Y14 R0

Leading scorer Milner 4

Manchester United

Subs from Romero, Johnstone, Rojo, Depay, Rooney, Young, Fosu-Mensah, Tuanzebe, Schneiderlin, Darmian, Martial, Mkhitaryan, Shaw

Doubtful None

Injured Jones (knee, Nov)

Suspended None

Form WWLLWD

Discipline Y14 R0

Leading scorer Ibrahimovic 4