Few would have predicted Southampton would find themselves above the champions after seven games of the season. Mauricio Pochettino's side have prospered thanks to a solid defence and from securing key victories, such as their 1-0 triumph against Liverpool. United won at Sunderland in their last outing with a double from Adnan Januzaj and he is likely to feature again. John Stephens
Kick-off Saturday 3pm
Venue Old Trafford
Last season Man Utd 2 Southampton 1
Referee M Jones
This season G2, Y4, R1, 3.0 cards per game
Odds H 6-11 A 6-1 D 10-3
Manchester United
Subs from Lindegaard, Buttner, Jones, Evans, F da Silva, Welbeck, Anderson, Cleverley, Zaha, Giggs, Smalling, Kagawa, Valencia, Hernández
Doubtful Ferdinand (groin), Cleverley (calf)
Injured Fletcher (bowel, unknown)
Suspended None
Form WLLWLD
Discipline Y17 R0
Leading scorers Rooney, Van Persie 3
Southampton
Subs from K Davis, Gazzaniga, Fox, Yoshida, Rodriguez, Ramírez, Cork, Ward-Prowse, Lee, Do Prado, Hooiveld, Stephens, Chambers, Isgrove
Doubtful Boruc
Injured None
Suspended None
Form WWWDLD
Discipline Y8 R0
Leading scorer Lambert 2