1 Twickenham is not in Wales. It does not have a roof, nor a frenzied congregation loudly supporting England's rivals. The Millennium Stadium factor will not apply.

2 Last year's game was less one-sided than the scoreline indicated. Manu Tuilagi's first-half fumble transformed the contest and England were still within six points with 30 minutes to go.

3 It is 36 years since Wales won two championship games in a row at Twickenham.

4 England are a significantly better team 12 months on.

5 Wales are not quite the same dominant force.

6 The Welsh were much improved against France but, let's face it, the French were rubbish.

7 No team has ever won a hat-trick of Six Nations titles.

8 England are supremely motivated after last year's outcome. Revenge is a dish best served with a chilled bottle of white wine in the West Car Park, as the old saying goes.

9 Only six of the England XV last year will be starting this Sunday.

10 Wales may have 12 Lions in their starting line-up but England's assistant coaches Andy Farrell and Graham Rowntree also shared in last summer's series win and know their visitors inside out.

11 Those English players overlooked by the Lions selectors are extremely keen to show Warren Gatland what he missed.

12 England are averaging fewer than 10 penalties per game in the Six Nations this year, potentially neutralising the influence of Leigh Halfpenny's deadly boot.

13 Last month's win over Ireland also suggested that England's younger players are responding more positively to last-quarter pressure.

14 The change in the scrummaging laws makes it harder to destroy opposing Test front rows. Wales' tighthead Adam Jones has not been as consistently dominant this season.

15 Steve Walsh is not refereeing. England felt he did them no favours in Cardiff and he was also in charge of Wales' victory in this same fixture in 2012.

16 Steve Walsh is an assistant referee on Sunday. He will be very keen to secure a gig at next year's World Cup, so cannot afford to get involved in fresh controversy.

17 Wales were thrashed 26-3 by Ireland in their last away game, the very same Ireland side England have just defeated.

18 Jonathan Davies is a top centre but he is only just back from a lengthy injury lay-off. It is asking a lot to expect him to sparkle against England.

19 Joe Launchbury is currently performing as well as any forward in the Six Nations. Courtney Lawes is not far behind. Not everyone in Wales appears to have noticed.

20 England's attempts to connect with their home supporters, including the longer walk from their bus to dressing room and displaying fans' messages in the tunnel, seemed to have the desired effect against the Irish. Chris Robshaw and his players look increasingly comfortable at Twickenham.

21 The referee, Romain Poite, has refereed only one previous Six Nations game at Twickenham, in 2011. England won it.

22 England could be going for a grand slam save for two wicked bounces of the ball in Paris. They are due a bit of luck – not to mention a first triple crown since 2003 – against Wales.

23 George North now plays his rugby for Northampton, alongside Luther Burrell, Tom Wood, Courtney Lawes and Dylan Hartley. As Burrell has made clear, they know precisely how best to deal with him.

24 England do not have Chris Ashton playing on their wing. Wales will have to look elsewhere for a potentially weak defensive link.

25 Dylan Hartley and Richard Hibbard and Courtney Lawes and Alun Wyn Jones have met twice this season already, home and away. Northampton beat the Ospreys on both occasions.

26 Owen Farrell has given up ill-discipline for Lent.

27 Last time England had a six-day turnaround prior to the Welsh game. This year they have enjoyed a fortnight of meticulous preparation.

28 England and Wales will next meet at Twickenham in the 2015 World Cup pool stages. The host nation are not about to lose at home by 30 points under those circumstances.

29 Jonny May will not drop the ball over the try-line twice in two games.

30 England have never lost at home on the penultimate weekend of a Six Nations championship. They have played at Twickenham nine times in round four and won the lot.

And three reasons why not ...

1 See the reasons to numbers three and seven above.

2 Warren Gatland specialises in spectacular results in big games at Twickenham.

3 Welsh rugby players absolutely love articles like this one.